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Topically applied copper peptides, in concentrations up to 4%, are generally considered safe and well tolerated by all skin types

The 2006 study by Teichman et al involved administering CJC-1295 DAC to test subjects in weekly or biweekly dosages of between 30 g/kg and 60 g/kg [2]

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Front Mol Biosci 5:105 Murayama R, Kimura-Asami M, Togo-Ohno M, Yamasaki-Kato Y, Naruse TK, Yamamoto T, Hayashi T, Ai T, Spoonamore KG, Kovacs RJ, Vatta M, Iizuka M, Saito M, Wani S, Hiraoka Y, Kimura A, Kuroyanagi H (2018) Phosphorylation of the RSRSP stretch is critical for splicing regulation by RNA-Binding Motif Protein 20 (RBM20) through nuclear localization